The modern dairy industry, bacteriophage contamination , a frequent concern during the production of fermented dairy products, is akin to a "biological crisis." Traditional CIP (Clean-In-Place) procedures are completely ineffective against lactic acid bacteria bacteriophages, and even the 90°C, 15-minute inactivation method recommended by the International Dairy Federation proves ineffective, as some bacteriophages can still survive. Therefore, many lactic acid bacteria producers often find themselves powerless to address this issue.
For a long time, the dairy industry's main methods for dealing with bacteriophages have focused on strain rotation and physical isolation , and even traditional disinfection methods have repeatedly proven ineffective. Therefore, for this bacteriophage with its extremely simple structure and dense outer shell, the key to solving the problem lies in how to overcome its strong resistance to the external environment through the combination of its protein capsid and internal nucleic acid (DNA/RNA) .
This phenomenon can easily lead to a contamination outbreak, causing the fermentation broth's OD value to stagnate, the pH value to rise, and even the entire tank to become contaminated. If traditional chlorine-based disinfectants are used, they cannot penetrate the bacteriophage's outer layer, and tons of raw milk will still be wasted, inevitably causing even more serious and huge losses.

In the event of contamination and emergency production, the usual procedure is to transfer the waste to another container, followed by heating at a high temperature of > 90℃ , or cleaning with caustic soda circulation.
This problem is often defined as "increased production without increased profits," and this hidden danger has remained unresolved throughout the industry's development. Since traditional passive defensive strategies are ineffective, we should intervene directly at the source.
It was through this strategic improvement that the properties of chlorine dioxide were amplified. The dairy industry has also continuously updated its standards in line with the iteration of disinfection technologies. In September 2025, the official implementation of the new national standard GB19302-2025 raised the hygiene standards for fermented dairy product production to a new level. Xiuba chlorine dioxide disinfectant brand believes it has the capability to play this indispensable role as a production shield.
Chlorine dioxide disinfectant essentially provides an active oxidation control mechanism, directly penetrating and destroying the target bacteria. Xiuba chlorine dioxide provides a perfect logical parallel to the application of anti-phage fermentation agents described in the *Food Safety Guide*. By precisely controlling the concentration and dosage, it directly captures and inactivates the culprit at the molecular level, precisely controlling the pain point of "slow fermentation" caused by phage contamination. Therefore, chlorine dioxide is precisely the scientific solution to this disinfection problem.

effective research by Russian researchers , chlorine dioxide disinfectant can kill virulent free bacteriophages . Using concentrations of 33.0 mg/L to 132.0 mg/L can exert its direct killing effect on bacteria and spores , effectively eliminating host bacteria carrying prophages, demonstrating a unique strangulation and obstacle -clearing ability .
In dairy companies' sterilization systems, the CIP (Clean-In-Place) pipeline cleaning process is particularly critical. When using Xiuba chlorine dioxide disinfectant, only 33.0 mg/dm³ is needed to kill various bacteria . If the raw materials contain mixed lactococcal phages , even at concentrations as high as 10⁵ PFU/cm³ , the disinfectant concentration needs to be increased to 49.5 mg/dm³ (equivalent to 1.5% of the formulation concentration) . Even if more than 10 different genotypes of lactococcal phages are mixed , they can be eliminated in one treatment . Xiuba chlorine dioxide perfectly matches the actual sterilization needs of production, using a scientifically proportioned method for precise disinfection.
bacteriophages after 24 hours . Xiuba's solution is to spray chlorine dioxide disinfectant through atomization equipment, allowing chlorine dioxide molecules to continuously disinfect all contact surfaces in the fermentation workshop. This not only meets the new national standards for production environments but also avoids the lengthy process and potential hidden damage to equipment associated with traditional disinfection methods.

The brand value of Xiuba chlorine dioxide disinfectant is self-evident. It fully leverages chlorine dioxide's ability to penetrate cell membrane barriers, optimizing the environment and eliminating potential hazards at the production front end, making CIP cleaning in dairy processing effortless. This allows companies to achieve stable output without incurring hidden raw material costs and waste – the reliable and certain production that dairy industry professionals experience. With the in-depth implementation of new national standards such as GB 19302-2025 "Fermented Milk," Xiuba chlorine dioxide disinfectant has developed a comprehensive, three-dimensional disinfection and protection barrier covering "air-surface-pipeline," easily enabling dairy fermentation companies to achieve substantial improvements in GMP (Good Manufacturing Practices).
Xiuba chlorine dioxide disinfectant plays a frontline defensive role, acting as a reliable gatekeeper for enterprise safety production.